The 56-year-old singer is set to take the stage at the London music ceremony on 25 February to perform a medley of hits.
Her turn on stage will mark 20 years since her last performance when, in 1995, she belted out her top 5 single Bedtime Stories for fans.
This year, the star will give the audience a show-stopping preview of her thirteenth studio album – Rebel Heart – set to be released in March.
Madonna has had 12 BRIT Award nominations in total, including two wins in 2001 and 2006, both for Best International Female.The award-winning singer now joins a seriously star-studded line up including Taylor Swift, Sam Smith, Ed Sheeran, and Take That at the award ceremony.
BRITs Chairman Max Lousada said: “We’re delighted to bring Madonna back to the BRITS. She’s an icon, an innovator and, above all, an entertainer.Having her as part of the show will guarantee an unforgettable night of music.”
With over 30 million albums sold worldwide, the mother-of-four will no doubt cause a stir when she takes to the stage.
The artist took to Twitter this afternoon to confirm the news, she said: “Hello to all my UK Rebel Hearts!!! See you at the Brits on Feb 25th #BritsImMadonna #livingforlove #rebelheart”
The BRIT Awards 2015 will be held at The O2 in London on Wednesday 25 February and will be broadcast live on ITV.